The CRUSADE National Quality Improvement Initiative: Characteristics, Management, and Outcomes of 5,557 Patients Age ≥90 Years With Acute Coronary Syndromes. Adam H. Skolnick, MD.

Evaluation by Optical Coherence Tomography (OCT) of Neointimal Coverage of Sirolimus-Eluting Stent Three Months After Implantation Masamichi Takano, MD. et al

Analysis of 36 Reported Cases of Late Thrombosis in Drug-Eluting Stents Placed in Coronary Arteries. Ramin Artang, MD and Robert S. Dieter, MD. et al

TAXUS ATLAS WORKHORSE and DIRECT STENT First Report of Nine and Twelve Month Clinical and Angiographic Results. Mark A. Turco, MD and John A. Ormiston, MBChB

Randomized Early versus Late AbciXimab in Acute Myocardial Infarction treated with primary coronary intervention (RELAx-AMI Trial) Mauro Maioli, M.D>

Clinical Implications of Clopidogrel non-responsiveness.  Dominick Angiolillo, MD, PhD

Post-Conditioning the Human Heart to Reduce Infarct Size. Michel Ovize, MD, PhD.

ACUITY 1 Year Results  A Prospective, Randomized Trial of Bivalirudin in Acute Coronary Syndromes Final One-Year Results from the ACUITY Trial. Gregg W. Stone, MD

Randomized Double Blind Trial of Thrombin Receptor Antagonist (TRA) Moliterno et al

ARMYDA-ACS: Atorvastatin Pretreatment Improves Outcome in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention

TRIUMPH The Tilarginine Acetate Injection in a Randomized International Study in Unstable Acute Myocardial Infarction Patients with Cardiogenic Shock Trial. Judith S. Hochman, M.D.

ARISE Aggressive Reduction of Inflammation Stops Events. Presented by Dr. Jean-Claude Tardif

Cardiovascular Risk with COX-IIs - MEDAL Program: Multinational Etoricoxib and Diclofenac Arthritis Long-term. Christopher P. Cannon, MD

Aliskiren and Valsartan for Antihypertensive Therapy. Presented by Dr. Suzanne Oparil

ECLIPSE Blood Pressure Control with Clevidipine Compared with Nitroglycerin, Sodium Nitroprusside, or Nicardipine in the Treatment of Peri-operative Hypertension Solomon Aronson, M.D.

ECLIPSE BP Control Blood Pressure Control is an Independent Predictor of Short-term Mortality in Cardiac Surgery Patients. Solomon Aronson, M.D.

RACE: Reperfusion in AMI in Carolina Emergency Departments. Christopher Granger, MD.

OASIS 6: Efficacy and safety of fondaparinux in elderly patients with STEMI. Ron J.G. Peters, MD.

Implications of Preoperative Thienopyridine Use Prior to Coronary Bypass Graft Surgery in Patients with ACS: A Report from the ACUITY Trial. Ramin Ebrahimi, MD.

ANTHEM-TIMI 32: Results of the Dose- Ranging and Heparin De-Escalation Phases of the ANTHEM-TIMI 32 Trial. Robert P. Giugliano, MD, SM.

ABSORB First-ever human trial of a fully bioabsorbable everolimus-eluting stent. Presented by Dr. Patrick W. Serruys

DEDICATION Distal protection using a Filterwire compared with conventional intervention among patients with STEMI undergoing PCI. Presented by Dr. Leif Thuesen.

ERASE Effect of rHDL on Atherosclerosis-Safety and Efficacy. Presented by Dr. Jean-Claude Tardif.

ILLUSTRATE Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation. Presented by Dr. Steven E. Nissen.

METEOR Measuring Effects of Intima-Media Thickness: An Evaluation of Rosuvastatin. Presented by Dr. John R. Crouse III. View an animated presentation.  View other resources

NAPA Nesiritide Administered Peri-Anesthesia in Patients Undergoing Cardiac Surgery. Mark J. Russo, MD, MS.

SPIRIT III  Clinical, Angiographic, and IVUS Results from the Pivotal U.S. Randomized SPIRIT III Trial of the XIENCE V Everolimus-eluting Coronary Stent System.  Gregg W. Stone, MD.

FUSION II Follow-Up Serial Infusions of Nesiritide for the Management of Patients With Heart Failure.

EVEREST Efficacy of Vasopressin antagonism in hEart failuRE: outcome Study with Tolvaptan (EVEREST).  Marvin A. Konstam, MD

ACC 2007 In Review

Top Ten Clinical Trials of the Year: 2006

Emerging Data Regarding the Potential Benefits of Early Initiation of Clopidogrel Among ACS Patients. C. Michael Gibson, M.S., M.D.

New Approaches to Chronic Anticoagulation: Factor XA Inhibition. C. Michael Gibson, MS, MD.

LDL or HDL: Which is More Important?  Christopher P. Cannon, MD

Is It Safe To Switch Between Antithrombins? C. Michael Gibson, M.S., M.D.

Antiplatelet Therapy in ACS and PCI: Challenges and Future Directions. Stephen D. Wiviott, MD.

Incorporating Patient Risk into Decisions Regarding the Optimal Reperfusion Strategy for ST Elevation MI. Duane S. Pinto, MD.

Appropriate Use of Lytics: Adherence to the Guidelines. W. Frank Peacock, MD, FACEP.

Pretreatment with Thienopyridines: Emerging Data Regarding the Potential Benefits of Early Initiation of Clopidogrel Among ACS Patients.  C. Michael Gibson, MS, MD

Targeting Hemoglobin and the Use of Erythropoietin and Transfusion in Cardiac Patients. Peter A. McCullough, MD, MPH, FACC, FACP.

Prognostic Implications of Bleeding and Transfusions in Acute Coronary Syndromes and Percutaneous Coronary Intervention. Steven V. Manoukian, M.D., F.A.C.C., F.S.C.A.I.

10 Lessons Learned from CRUSADE: Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC and AHA Guidelines?  Eric D. Peterson, MD, FACC.

Coronary Revascularization in Diabetic Patients: Optimizing Outcomes in 2007. David J. Cohen, M.D., M.Sc.

Effect of Aspirin Dose on Platelet Reactivity in Diabetic Patients. Paul A. Gurbel, MD.

Are all Xa Inhibitors the Same?  Alexander G. G. Turpie, M.D.

Pay For Performance: What Does it Mean, What will be its Impact in CV Care. James Hoekstra, MD

Toxicity and Screening Recommendations for Amiodarone Use. Peter Zimetbaum, MD, FACC.

The Balancing Act in ACS Continues – But with Better Outcomes? Shamir Mehta, MD, MSc, FRCPC

ACUITY Timing Results Presented by Dr. G Stone

10 TIMI Lessons

Completed TIMI Trials

Recently Completed TIMI Trials

Ongoing TIMI Trial Designs

CLEAR PLATELETS Ib: A Mechanistic Link Between High Platelet Reactivity, Inflammation Marker Release and Myonecrosis in Patients Undergoing Stenting

CREATE The Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy Trial

EPIC-Norfolk Prospective Population Study: Value of Lipoprotein Particle Number and Size as Predictors of Coronary Artery Disease in Apparently Healthy Men and Women

GRACIA-2: Primary Optical Percutaneous Coronary Intervention Versus Facilitated Intervention in STEMI Patients

RAAVE: Rosuvastatin Affecting Aortic Valve Endothelium to Slow the Progressions of Aortic Stenosis

AFIST III:  Impact of Epicardial Anterior Fat Pad Retention on Postcardiothoracic Surgery Atrial Fibrillation Incidence

Clopidogrel Use and Long-term Clinical Outcomes after Drug Eluting Stent Implantation:  Eisenstein et al.

The PIOSTAT Study:  Anti-Inflammatory Effects of Pioglitazone and/or Simvastatin in High Cardiovascular Risk Patients With Elevated High Sensitivity C-Reactive Protein

Prevention of Premature Discontinuation of Dual Antiplatelet Therapy in Patients with Coronary Artery Stents:  Grines CL, et al.

Rescue Angioplasty or Repeat Fibrinolysis After Failed Fibrinolytic Therapy for ST-Segment Myocardial Infarction: A Meta-Analysis of Randomized Trials:  Wijeysundera HC, et al.

Association of DES with Impaired Collateral Function Meier et al,

Dopamine Agonists and the Risk of Cardiac Valve Regurgitation Schade, et al

Valvular Heart Disease and the Use of Dopamine Agonists for Parkinson’s Disease, Zanettini et al,