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Reperfusion Injury


         -Glucose Insulin Potassium

         -Aqueous Oxygen Therapy

Anti-Inflammatory Approaches


Acute Myocardial Infarction:

      -Role of Adenosine in Acute Myocardial Infarction by Dr. Mervyn B. Forman

AMISTAD II: Acute Myocardial Infarction Study of Adenosine

      -Trial Overview

CREATE-ECLA-GIK: The Clinical Trial of Reviparin and Metabolic Modulation in Acute Myocardial Infarction Treatment Evaluation - Estudios Cardiológicos Latinoamérica - Glucose-Insulin-Potassium

      -No Improvement in 30-day Mortality with High-dose Glucose-Insulin-Potassium (GIK) Infusion by Dr. S.R. Mehta (AHA 2004)

GIPS II: Glucose-Insulin-Potassium Study-2

      -In Patients with ST Elevation Myocardial Infarction Without Signs of Heart Failure by Dr. Jorik Timmer (ACC 2005)

IMMEDIATE: Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care: A Double-Blind Randomized Controlled Trial of Intravenous Glucose, Insulin, and Potassium (GIK) for Acute Coronary Syndromes in Emergency Medical Services

      - Trial Results by Dr. Harry P. Selker (ACC 2012)

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Cold Saline and Endovascular Cooling

      -Rapid Hypothermia Before Reperfusion in STEMI Patients Treated With Primary PCI by Dr. David Erlinge (TCT 2010)


Cool MI Feasibility

      -COOLing as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Hypothermia in STEMI

      -"Cool It": Therapeutic Hypothermia for Recovery of Neurologic Function in High Risk Patients Following Cardiac Arrest by Dr. Leah A. Swanson (2009)

- Aqueous Oxygen Therapy

AMIHOT: Acute Myocardial Infarction with Hyperoxemic Therapy

      -Aqueous Oxygen Therapy Improves ST-Segment Resolution in Anterior Myocardial Infarction by Dr. J.L Martin (TCT 2004)

- Post-Conditioning

Infarct Size

      -Post-conditioning the Human Heart to Reduce Infarct Size by Dr. Michel Ovize

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 Anti-Inflammatory Approaches

APEX AMI: Assessment of Pexelizumab in Acute Myocardial Infarction

      -Trial Overview by Dr. Armstrong (2007)

LIMIT AMI: LImitation of Myocardial Injury following Thrombolysis in Acute Myocaridal Infarction

      -An Angiographic Safety and Efficacy Trial of a Novel Anti-CD18 Therapy in Acute Myocardial Infarction in Conjunction with Thrombolysis by Dr. Kenneth W. Baran (2000)

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