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ST Elevation Myocardial Infarction (STEMI) |
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Summary Slides
Download Results of TIMI Trials 1-17 Over 80 slides from the past 15 years of TIMI trials all in one slide set
Door to Balloon Times and Mortality
Overview of Phase II Angiographic Trials of Combination Therapy with full dose GPIIbIIIa inhibition plus reduced dose fibrinolysis
Commentary on the COMMIT Trial of 46,000 patients randomized to Lopressor in STEMI
Commentary on the COMMIT Trial of 46,000 patients randomized to Plavix in STEMI
Slideset based upon the AHA/ACC STEMI Guidelines Recommendations
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Pharmacologic Management
Fibrinolytic Monotherapy: ASSENT 2 TNK in STEMI
ASSENT-3 TNK in STEMI
ASSENT 3-PLUS Low molecular weight heparin enoxaparin vs unfractionated heparin in combination with TNK for STEMI
ASSENT 4 Assessment of the Safety and Efficacy of a New Treatment Strategy for Acute Myocardial Infarction
CLARITY-TIMI 28 Largest Angiographic ST Elevation MI Trial to Date Shows Improved Patency & Myocardial Perfusion with Plavix
COMMIT Clopidogrel Clopidogrel vs placebo among patients with ST elevation myocardial infarction (MI) also treated with aspirin
COMMIT Lopressor Treatment with the beta-blocker metoprolol compared with placebo among patients with STEMI also treated with aspirin
CREATE-Reviparin Trial of low molecular wt. heparin oid in STEMI
ENTIRE Phase 2 study of Enoxaparin in STEMI
EXTRACT-TIMI 25 Enox vs UFH in 20,000 STEMI pts provided by Dr. Elliott M. Antman
HART 2 Enoxaparin in STEMI
TIMI 10A, 10B, ASSENT I TNK in STEMI Half Dose Fibrinolytic + Full Dose GPIIbIIIa inhibition:
FASTER Aggrastat in STEMI
GUSTO 5 trial design rPA + abciximab vs rPA alone in STEMI
INTEGRITI Eptifibatide + TNK in STEMI
INTRO AMI Rationale Eptifibatide + lysis in STEMI
INTRO AMI Results Eptifibatide + lysis in STEMI
SPEED rPA + abciximab
TIMI 14 rPA + abciximab in STEMI Other: Intracoronary Autologous Bone-Marrow Cell Transfer after Myocardial Infarction
PREAMI Perindopril Remodeling in Elderly With Acute Myocardial Infarction
PREMIER Matrix Metalloproteinase Inhibitor to Prevent Left Ventricular Remodeling After Acute Myocardial Infarction |
Interventional Strategies
Primary PCI: ALKK PTCA in stable survivors of acute MI vs medical therapy
BRAVE-2 Benefit of primary PCI among asymptomatic pts presenting late in STEMI
CADILLAC Abciximab & Bare Metal Stenting in STEMI
CAPTIM Comparison of Angioplasty and Prehospital Thrombolysis in Acute Myocardial Infarction
DANAMI II Danish Myocardial Infarction Study
MATE from Peter McCullough, M.D., Medicine vs Angiography in Thrombolytic (Reperfusion) Exclusion Patients
PAMI Stent: Mortality among patients with a closed artery on presentation to cath lab
WEST: Which Early ST Elevation Myocardial Infarction Therapy Trial Facilitated PCI: ADMIRAL Abciximab pre-PCI for STEMI
ADVANCE Additive value of tirofiban administered with the high-dose bolus in the prevention of ischemic complications during high-risk coronary angioplasty *Provided by Dr. Valgimigli, University of Ferrara Italy & Erasmus MC, the Netherlands
CAPITAL AMI Combined Angioplasty and Pharmacological Intervention Versus Thrombolytics Alone in Acute Myocardial Infarction
GRACIA-2 Safety and efficacy of optimal primary PCI vs facilitated PCI with TNK+stenting in patients with ST elevation MI
INTAMI Integrilin in Acute Myocardial Infarction
PACT Half dose tPA before PCI in STEMI
REACT Rescue Angioplasty Versus Conservative Therapy or Repeat Thrombolysis Trial
STRATEGY Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent vs. Abciximab and Bare-Metal Stent in Myocardial Infarction
TETAMI Treatment of Enoxaparin and Tirofiban in Acute Myocardial Infarction
TIGER PA Aggrastat before primary PCI
Distal Protection:
AiMI Thrombectomy With the AngioJet in Acute Myocardial Infarction
EMERALD Enhanced Myocardial Efficacy and Removal by Aspiration of Liberated Debris
Filterwire FilterWire-Ex as an Adjunct to Primary PCI |